ANTKMT

Across TCGA patient cohorts, ANTKMT mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible ANTKMT-associated genes across cancer lineages are RNA5SP472, RNU6-259P, and RNA5SP407. Each is linked with ANTKMT in more than 1 cancer types. Because this analysis shows association rather than direction, both ANTKMT-to-partner and partner-to-ANTKMT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP472 grouped by ANTKMT-low versus ANTKMT-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANTKMT→partner) and Y-score (partner→ANTKMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP472 →	+0.301	+7.924	<.001	.008	3	1
LUSC	RNU6-259P →	+0.391	+7.924	<.001	.008	3	1
LUSC	RNA5SP407 →	+0.633	+7.924	<.001	.008	3	1
LUSC	RNA5SP518 →	+0.358	+7.924	<.001	.008	3	1
LUSC	RNU6-1270P →	+0.388	+7.924	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

RNA5SP472 by ANTKMT expression — LUSC

Explore this box plot interactively →