ANTKMT

Across TCGA pan-cancer cohorts, ANTKMT RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated ANTKMT data layer compared with 1 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ANTKMT RNA is associated with better overall survival. In most high-consensus cancer types, elevated ANTKMT expression acts as an unfavorable survival marker, although some lineages such as HNSC and SARC show a favorable association.

HNSC, UVM, and UCS are the cancer types where ANTKMT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.840	0.714	.003	72	view →
UVM	OS	Quartile	All	0.356	0.854	.001	59	view →
UCS	OS	Median	IV	0.224	0.732	.018	48	view →
ACC	OS	Quartile	All	0.766	1.000	.001	37	view →
LUAD	DFS	Tertile	All	0.602	0.726	.003	32	view →
KIRC	DFS	Tertile	All	0.768	0.856	.012	27	view →
COAD	OS	Median	II,III,IV	0.524	0.729	.008	26	view →
SARC	OS	Median	All	0.860	0.672	.005	23	view →
BLCA	OS	Quartile	All	0.800	0.635	.007	22	view →
LGG	DFS	Median	All	0.667	0.798	<.001	21	view →
KICH	DFS	Median	All	0.946	0.709	.008	18	view →
PRAD	DFS	Median	All	0.678	0.901	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

ANTKMT–HNSC (OS)

Open the HNSC breakdown →