Q-omics provides the consensus-scored RNU6-259P profile across patient tissues and cancer cell-line models. RNU6-259P expression is associated with patient survival in 4 of 34 cancer types, with the highest sampling consensus in KIRC. Additionally, RNU6-259P RNA expression shows 8,063 significant gene co-expression associations, with the highest sampling consensus in LUSC. Together, these results highlight KIRC, and LUSC as cancer lineages where RNU6-259P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU6-259P survival associations across molecular data types. RNU6-259P RNA expression shows survival associations in the most cancer types (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-259P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	4	KIRC (138)	view →

This table ranks reproducible RNU6-259P RNA expression–survival associations across cancer types. High RNU6-259P expression shows unfavorable associations in KIRC, UCEC, PAAD and GBM. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for RNU6-259P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.490	0.809	<.001	138	view →
UCEC	OS	Tertile	All	0.116	0.679	.008	36	view →
PAAD	OS	Tertile	II,III,IV	0.213	0.556	.014	36	view →
GBM	OS	Tertile	All	0.178	0.420	.017	9	view →

Pink = unfavorable, green = favorable. all 4 lineages →

RNU6-259P-KIRC (OS)

Kaplan–Meier survival curve for RNU6-259P RNA expression in KIRC: high vs low expression groups.

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Cross-omics associations

This table shows molecular features associated with RNU6-259P in patient tissues and cancer cell lines. In patient samples, RNU6-259P shows the broadest associations at the RNA and protein expression levels, with LUSC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	8,063	LUSC (4562)	view →
Function (RNA)	5,734	STAD (5664)	view →