ANP32D

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANP32D mutation is significantly associated with the RNA expression of many other genes, with 159 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ANP32D-associated genes across cancer lineages are AQP7P5, MIR3690, and RNU6ATAC14P. Each is linked with ANP32D in more than 1 cancer types. Because this analysis shows association rather than direction, both ANP32D-to-partner and partner-to-ANP32D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AQP7P5 grouped by ANP32D-low versus ANP32D-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANP32D→partner) and Y-score (partner→ANP32D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMAQP7P5 →+0.051+2.547.002.00932
UCECMIR3690 →+0.620+3.224<.001.00132
UCECRNU6ATAC14P →+0.705+3.048<.001.00232
BLCARNA5SP125 →+0.266+5.588.002.00432
SKCMOR5W2 →+0.043+3.122<.001.00232
SKCMRNU6-732P →+0.146+4.025<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 159 associations by consensus.

AQP7P5 by ANP32D expression — SKCM

Box plot of AQP7P5 in ANP32D-low vs ANP32D-high samples in SKCM.

Explore this box plot interactively →

Exploration