ANP32D

Across TCGA pan-cancer cohorts, ANP32D RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated ANP32D data layer compared with 5 for mutation status.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher ANP32D RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ANP32D expression acts as an unfavorable survival marker, although some lineages such as BLCA and GBM show a favorable association.

DLBC, LIHC, and BLCA are the cancer types where ANP32D RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Quartile	II,III,IV	0.251	1.000	.002	75	view →
LIHC	DFS	Tertile	All	0.462	0.576	.013	25	view →
BLCA	DFS	Tertile	III,IV	0.540	0.278	.012	23	view →
GBM	DFS	Median	All	0.387	0.201	.005	23	view →
LUAD	DFS	Median	All	0.478	0.230	.002	18	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
KIRP	OS	Median	III,IV	0.868	0.365	.007	14	view →
OV	OS	Median	II,III,IV	0.289	0.358	.026	12	view →
READ	DFS	Median	IV	0.397	0.822	.011	9	view →
COAD	OS	Quartile	IV	0.200	0.775	.001	9	view →
ESCA	OS	Tertile	IV	0.738	0.243	.024	6	view →
LAML	DFS	Median	All	0.269	0.502	.033	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

ANP32D–DLBC (OS)

Open the DLBC breakdown →