ANO8

Across TCGA patient cohorts, ANO8 protein abundance is significantly associated with the RNA expression of many other genes, with 5,818 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ANO8-associated genes across cancer lineages are ZNF398, LAMB2P1, and TNPO2. Each is linked with ANO8 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANO8-to-partner and partner-to-ANO8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANO8 versus ZNF398 in HNSC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANO8→partner) and Y-score (partner→ANO8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZNF398 →	+0.785	+0.828	.003	.006	3	4
HNSC	LAMB2P1 →	+1.141	+0.869	.003	.004	3	4
LSCC	TNPO2 →	+0.505	+0.373	<.001	<.001	3	3
LSCC	GCDH →	+0.689	+0.483	<.001	<.001	3	3
GBM	RAB3A →	+0.939	+0.241	<.001	.001	3	3
GBM	SUGP1 →	+0.421	+0.266	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,818 associations by consensus.

ANO8 vs ZNF398 — HNSC

Explore this scatter interactively →