Q-omics provides the consensus-scored LAMB2P1 profile across patient tissues and cancer cell-line models. LAMB2P1 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, LAMB2P1 is differentially expressed in 11, with the highest sampling consensus in THCA. Additionally, LAMB2P1 RNA expression shows 20,309 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight UVM, THCA, and GBM as cancer lineages where LAMB2P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LAMB2P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LAMB2P1 survival associations across molecular data types. LAMB2P1 RNA expression shows survival associations in the most cancer types (25). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LAMB2P1 RNA expression–survival associations across cancer types. High LAMB2P1 expression shows unfavorable associations in ACC and COAD, but favorable associations in UVM, SKCM, HNSC and LGG. The UVM Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for LAMB2P1 RNA expression.
This table summarizes LAMB2P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for LAMB2P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LAMB2P1 shows lower tumor expression in THCA, LUAD, UCEC and BRCA and higher tumor expression in LIHC and CHOL. The THCA box plot shows higher LAMB2P1 RNA expression in normal versus tumor tissue (log2 FC = −0.916, t-test p < 0.001).
This table shows molecular features associated with LAMB2P1 in patient tissues and cancer cell lines. In patient samples, LAMB2P1 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
