Across TCGA patient cohorts, ANKUB1 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKUB1-associated genes across cancer lineages are EGFR, ERCC1, and Ku80. Each is linked with ANKUB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKUB1-to-partner and partner-to-ANKUB1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKUB1→partner) and Y-score (partner→ANKUB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR →	-0.182	-3.321	.003	.010	3	1
UCEC	ERCC1 →	-0.151	-3.432	.025	.005	3	1
UCEC	Ku80 →	+0.234	+3.013	.011	.018	3	1
UCEC	MEK1 →	+0.448	+3.584	.001	.002	3	1
UCEC	Notch1 →	+0.147	+1.750	.007	.049	3	1
UCEC	Akt_pT308 →	+0.586	+2.321	.017	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

ANKUB1 survival (RNA) · tumor vs normal (RNA) · all ANKUB1 data types