Across TCGA pan-cancer cohorts, ANKUB1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated ANKUB1 data layer compared with 1 for mutation status.
The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher ANKUB1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ANKUB1 expression acts as an unfavorable survival marker, although some lineages such as CESC and ESCA show a favorable association.
CESC, KIRC, and ACC are the cancer types where ANKUB1 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.