Across TCGA pan-cancer cohorts, ANKUB1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of ANKUB1’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where ANKUB1 RNA is repressed in tumor relative to normal tissue. In most cancer types ANKUB1 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.
LUAD, COAD, and LUSC are the cancer types where ANKUB1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ANKUB1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.