ANKRD9

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANKRD9 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ANKRD9-associated genes across cancer lineages are OR51G2, OR5M8, and CYLC1. Each is linked with ANKRD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD9-to-partner and partner-to-ANKRD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51G2 grouped by ANKRD9-low versus ANKRD9-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD9→partner) and Y-score (partner→ANKRD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaOR51G2 →+0.017+4.384<.001.00631
CNSOR5M8 →+0.022+5.754<.001.00231
CNSCYLC1 →+0.013+5.321<.001.00531
CNSFGF3 →+0.043+4.981<.001.00831
CNSFAM205C →+0.043+4.981<.001.00831
CNSOR8K3 →+0.013+5.754<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OR51G2 by ANKRD9 expression — BLOOD_Leukemia

Box plot of OR51G2 in ANKRD9-low vs ANKRD9-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration