ANKRD6

Across TCGA cell cohorts, ANKRD6 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible ANKRD6-associated genes across cancer lineages are MAGEB5, MYF6, and OR4E1. Each is linked with ANKRD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD6-to-partner and partner-to-ANKRD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB5 grouped by ANKRD6-low versus ANKRD6-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD6→partner) and Y-score (partner→ANKRD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
OESOPHAGUS	MYF6 →	+0.013	+4.906	<.001	.006	3	1
OESOPHAGUS	OR4E1 →	+0.016	+4.906	<.001	.006	3	1
URINARY_TRACT	PCDH11Y →	+0.016	+5.087	<.001	.004	3	1
LARGE_INTESTINE	MAGEB4 →	+0.012	+5.415	.009	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

MAGEB5 by ANKRD6 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →