ANKRD42

Across TCGA cell cohorts, ANKRD42 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD42-associated genes across cancer lineages are AVP, TBC1D21, and OR52H1. Each is linked with ANKRD42 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD42-to-partner and partner-to-ANKRD42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by ANKRD42-low versus ANKRD42-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD42→partner) and Y-score (partner→ANKRD42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AVP →	+0.041	+3.217	<.001	.006	3	1
LARGE_INTESTINE	TBC1D21 →	+0.008	+3.700	<.001	.009	3	1
LARGE_INTESTINE	OR52H1 →	+0.026	+3.669	<.001	<.001	3	1
LARGE_INTESTINE	AVPR1B →	+0.031	+3.716	<.001	.003	3	1
LARGE_INTESTINE	TMEM235 →	+0.010	+3.297	<.001	.002	3	1
LARGE_INTESTINE	TBR1 →	+0.034	+3.333	.004	.009	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

AVP by ANKRD42 expression — LARGE_INTESTINE

Explore this box plot interactively →