ANKRD42

Across TCGA pan-cancer cohorts, ANKRD42 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ANKRD42’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ANKRD42 RNA is repressed in tumor relative to normal tissue. In most cancer types ANKRD42 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and LIHC are the cancer types where ANKRD42 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ANKRD42 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	II,III,IV	−1.075	<.001	10	view →
THCA	Male	All	−0.487	<.001	9	view →
LIHC	All	All	+0.309	<.001	6	view →
BRCA	All	All	+0.304	<.001	6	view →
CHOL	Female	All	+1.443	<.001	5	view →
STAD	Male	II,III,IV	+0.724	<.001	5	view →
LUSC	Male	All	−0.477	<.001	5	view →
KIRP	All	IV	+0.519	.014	4	view →
COAD	Male	II,III,IV	+0.330	.002	4	view →
PAAD	All	All	+0.512	.007	2	view →
PRAD	All	All	−0.218	.006	2	view →
COAD	Female	IV	−0.679	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ANKRD42–KICH

Open the KICH breakdown →