ANKRD36C

Across TCGA patient cohorts, ANKRD36C mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD36C-associated genes across cancer lineages are cIAP, p62 Lck ligand, and PDCD4. Each is linked with ANKRD36C in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD36C-to-partner and partner-to-ANKRD36C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, cIAP grouped by ANKRD36C-low versus ANKRD36C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD36C→partner) and Y-score (partner→ANKRD36C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	cIAP →	+0.081	+1.142	.041	.017	3	3
UCEC	p62 Lck ligand →	+0.375	+2.147	<.001	<.001	3	2
UCEC	PDCD4 →	-0.587	-3.169	<.001	<.001	3	2
UCEC	ATM →	-0.621	-3.234	<.001	<.001	3	2
UCEC	14-3-3_beta →	-0.096	-2.221	<.001	.001	3	1
UCEC	eEF2 →	+0.220	+1.807	.034	.024	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

cIAP by ANKRD36C expression — UCEC

Explore this box plot interactively →