ANKRD36C

Across TCGA pan-cancer cohorts, ANKRD36C RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated ANKRD36C data layer compared with 8 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ANKRD36C RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ANKRD36C expression acts as an unfavorable survival marker, although some lineages such as UCS and SKCM show a favorable association.

ACC, MESO, and KIRP are the cancer types where ANKRD36C RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.404	0.741	<.001	111	view →
MESO	OS	Median	III,IV	0.274	0.494	.001	88	view →
KIRP	DFS	Median	All	0.793	0.920	.001	52	view →
UCS	DFS	Median	IV	0.952	0.367	.001	46	view →
KIRC	DFS	Quartile	III,IV	0.238	0.636	.004	42	view →
SKCM	OS	Quartile	All	0.372	0.303	.002	39	view →
KICH	DFS	Quartile	II,III,IV	0.456	1.000	.001	33	view →
OV	DFS	Median	IV	0.308	0.615	<.001	32	view →
THCA	OS	Tertile	II,III,IV	0.750	0.981	.009	24	view →
READ	OS	Median	II,III,IV	0.775	0.456	.003	24	view →
HNSC	OS	Median	III,IV	0.468	0.283	.005	22	view →
UVM	DFS	Median	III,IV	0.267	0.796	.002	20	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

ANKRD36C–ACC (DFS)

Open the ACC breakdown →