Across TCGA pan-cancer cohorts, ANKRD36C RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of ANKRD36C’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ANKRD36C RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ANKRD36C is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.
KIRC, BRCA, and LUAD are the cancer types where ANKRD36C tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ANKRD36C RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.