ANKRD36C

Across TCGA cell cohorts, ANKRD36C mutation is significantly associated with the RNA expression of many other genes, with 145 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD36C-associated genes across cancer lineages are PRAMEF25, PAPOLB, and TMEM132C. Each is linked with ANKRD36C in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD36C-to-partner and partner-to-ANKRD36C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF25 grouped by ANKRD36C-low versus ANKRD36C-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD36C→partner) and Y-score (partner→ANKRD36C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	PRAMEF25 →	+0.090	+4.199	<.001	.007	3	2
STOMACH	PAPOLB →	+0.014	+4.794	<.001	.001	3	2
BLOOD_Lymphoma	TMEM132C →	+0.339	+3.736	<.001	.009	3	2
LUNG_NSCLC_LUAD	PRAM1 →	+0.260	+3.256	.002	.009	3	2
PANCREAS	VWA5B1 →	+0.227	+3.906	<.001	.002	3	1
PANCREAS	AGRP →	+0.086	+4.058	<.001	.001	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 145 associations by consensus.

PRAMEF25 by ANKRD36C expression — BREAST

Explore this box plot interactively →