ANKRD36C

Across TCGA cell cohorts, ANKRD36C mutation is significantly associated with the mutation status of many other genes, with 2,252 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD36C-associated genes across cancer lineages are PCDHB11, ADARB2, and STARD9. Each is linked with ANKRD36C in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKRD36C-to-partner and partner-to-ANKRD36C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCDHB11 grouped by ANKRD36C-low versus ANKRD36C-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD36C→partner) and Y-score (partner→ANKRD36C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PCDHB11 →	+3.509	+5.129	<.001	<.001	1	4
LUNG_NSCLC_LUAD	ADARB2 →	+3.662	+3.000	.007	.007	1	4
LUNG_SCLC	STARD9 →	+2.843	+4.193	.007	.007	1	4
SKIN	SCN9A →	+2.313	+3.282	.007	.007	1	4
LUNG_SCLC	NCAPG2 →	+5.066	+4.502	.007	.007	1	4
UPPER_AERODIGESTIVE_TRACT	SHANK2 →	+5.392	+5.392	.004	.004	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,252 associations by consensus.

PCDHB11 by ANKRD36C expression — SKIN

Explore this box plot interactively →