ANKRD31

Across TCGA cell cohorts, ANKRD31 mutation is significantly associated with the RNA expression of many other genes, with 408 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD31-associated genes across cancer lineages are DEUP1, C9orf50, and MRPS15. Each is linked with ANKRD31 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD31-to-partner and partner-to-ANKRD31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEUP1 grouped by ANKRD31-low versus ANKRD31-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD31→partner) and Y-score (partner→ANKRD31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DEUP1 →	+0.262	+3.754	<.001	.008	3	2
BLOOD_Lymphoma	C9orf50 →	+0.087	+4.070	<.001	.004	3	2
LARGE_INTESTINE	MRPS15 →	+0.457	+3.237	<.001	.003	3	2
LARGE_INTESTINE	GALR3 →	+0.076	+2.502	.001	.003	3	2
LARGE_INTESTINE	GRSF1 →	+0.512	+2.158	<.001	.004	3	2
LARGE_INTESTINE	MUTYH →	+0.746	+3.459	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 408 associations by consensus.

DEUP1 by ANKRD31 expression — BLOOD_Lymphoma

Explore this box plot interactively →