ANKRD31

Across TCGA pan-cancer cohorts, ANKRD31 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of ANKRD31’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where ANKRD31 RNA is repressed in tumor relative to normal tissue. In most cancer types ANKRD31 is over-expressed in tumor, although a few such as THCA and HNSC show the opposite, repressed pattern.

THCA, COAD, and HNSC are the cancer types where ANKRD31 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ANKRD31 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.220	<.001	10	view →
COAD	All	All	+0.074	<.001	9	view →
HNSC	All	IV	−0.428	.002	8	view →
STAD	All	All	−0.425	.007	4	view →
UCEC	All	All	−0.226	.009	4	view →
LUAD	All	All	+0.092	.010	4	view →
LIHC	All	All	+0.068	<.001	4	view →
KIRP	All	II,III,IV	+0.185	.035	3	view →
CHOL	All	All	+0.300	<.001	2	view →
READ	Female	All	+0.132	.025	2	view →
PRAD	All	All	−0.075	.009	2	view →
KIRC	All	All	+0.099	.018	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

ANKRD31–THCA

Open the THCA breakdown →