ANKRD30A

Across TCGA patient cohorts, ANKRD30A mutation is significantly associated with the total protein of many other genes, with 84 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD30A-associated genes across cancer lineages are Cyclin-B1, MSH6, and PCNA. Each is linked with ANKRD30A in more than 5 cancer types. Because this analysis shows association rather than direction, both ANKRD30A-to-partner and partner-to-ANKRD30A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by ANKRD30A-low versus ANKRD30A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD30A→partner) and Y-score (partner→ANKRD30A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.602	+1.509	<.001	<.001	3	6
COAD	MSH6 →	+0.436	+3.000	.010	.034	3	4
UCEC	PCNA →	+0.177	+2.000	.001	.002	3	4
LUSC	4E-BP1 →	+0.271	+1.691	.019	.011	3	3
STAD	ACVRL1 →	-0.229	-2.300	.018	.034	3	3
COAD	ERK2 →	+0.287	+2.484	<.001	.010	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 84 associations by consensus.

Cyclin-B1 by ANKRD30A expression — UCEC

Explore this box plot interactively →