ANKRD30A

Across TCGA cell cohorts, ANKRD30A mutation is significantly associated with the RNA expression of many other genes, with 540 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD30A-associated genes across cancer lineages are RAB3IP, RNFT2, and NBEAL2. Each is linked with ANKRD30A in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD30A-to-partner and partner-to-ANKRD30A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAB3IP grouped by ANKRD30A-low versus ANKRD30A-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD30A→partner) and Y-score (partner→ANKRD30A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	RAB3IP →	+0.756	+2.225	.002	.004	3	2
LUNG_NSCLC_LUAD	RNFT2 →	+0.761	+3.321	<.001	.004	3	2
LUNG_NSCLC_LUAD	NBEAL2 →	+0.863	+2.843	.001	<.001	3	2
LUNG_NSCLC_LUAD	RASGRP1 →	+0.627	+2.843	<.001	<.001	3	2
LUNG_NSCLC_LUAD	DYNC1I2 →	-0.520	-2.402	.001	.008	3	2
LUNG_NSCLC_LUAD	CDIP1 →	-0.916	-3.265	.006	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 540 associations by consensus.

RAB3IP by ANKRD30A expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →