ANKRD29

Across TCGA patient cohorts, ANKRD29 mutation is significantly associated with the RNA expression of many other genes, with 284 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD29-associated genes across cancer lineages are ZIC5, TLR5, and IGLJ5. Each is linked with ANKRD29 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD29-to-partner and partner-to-ANKRD29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZIC5 grouped by ANKRD29-low versus ANKRD29-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD29→partner) and Y-score (partner→ANKRD29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZIC5 →	+1.183	+2.793	<.001	.005	3	2
UCEC	TLR5 →	-0.958	-3.700	<.001	.001	3	2
UCEC	IGLJ5 →	+0.310	+3.063	<.001	.007	3	2
UCEC	LINC01072 →	+0.115	+2.640	.006	.003	3	2
BRCA	SDR42E1P1 →	+0.079	+9.057	<.001	.003	3	1
SKCM	VDAC1P3 →	+0.145	+2.928	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 284 associations by consensus.

ZIC5 by ANKRD29 expression — UCEC

Explore this box plot interactively →