ANKRD29

Across TCGA pan-cancer cohorts, ANKRD29 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ANKRD29 data layer compared with 5 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in uveal melanoma (UVM), where higher ANKRD29 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ANKRD29 expression acts as an unfavorable survival marker, although some lineages such as HNSC and KIRP show a favorable association.

UVM, HNSC, and KIRP are the cancer types where ANKRD29 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	II,III,IV	0.429	0.730	<.001	111	view →
HNSC	OS	Median	All	0.439	0.277	<.001	57	view →
KIRP	DFS	Median	All	1.000	0.783	.001	56	view →
BRCA	OS	Tertile	III,IV	0.915	0.737	<.001	52	view →
BLCA	OS	Tertile	All	0.396	0.651	.001	46	view →
ESCA	DFS	Median	III,IV	0.541	0.277	.001	43	view →
LUAD	OS	Median	All	0.750	0.618	<.001	35	view →
MESO	OS	Median	III,IV	0.250	0.757	.002	31	view →
SKCM	DFS	Median	All	0.250	0.159	.001	31	view →
CHOL	OS	Median	II,III,IV	0.903	0.382	.009	27	view →
LIHC	OS	Tertile	II,III,IV	0.879	0.598	.002	26	view →
ACC	DFS	Tertile	III,IV	0.156	0.581	.010	21	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ANKRD29–UVM (DFS)

Open the UVM breakdown →