voltage dependent anion channel 1 pseudogene 3Genealiases: []
Q-omics provides the consensus-scored VDAC1P3 profile across patient tissues and cancer cell-line models. VDAC1P3 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in BRCA. Among the 18 cancer types available for tumor–normal comparison, VDAC1P3 is differentially expressed in 5, with the highest sampling consensus in LUAD. Additionally, VDAC1P3 RNA expression shows 8,203 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight BRCA, LUAD, and GBM as cancer lineages where VDAC1P3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for VDAC1P3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes VDAC1P3 survival associations across molecular data types. VDAC1P3 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible VDAC1P3 RNA expression–survival associations across cancer types. High VDAC1P3 expression shows unfavorable associations in BRCA, ESCA, THCA, KICH and UVM, but favorable associations in CESC. The BRCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .018). Together, the overview and detailed table identify BRCA as the clearest survival context for VDAC1P3 RNA expression.
This table summarizes VDAC1P3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in LUAD for RNA.
This table ranks reproducible tumor–normal expression differences for VDAC1P3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. VDAC1P3 shows higher tumor expression in LUAD, COAD, BRCA, KICH and LIHC. The LUAD box plot shows higher VDAC1P3 RNA expression in tumor versus normal tissue (log2 FC = +0.073, t-test p = .001).
This table shows molecular features associated with VDAC1P3 in patient tissues and cancer cell lines. In patient samples, VDAC1P3 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
