Across TCGA cell cohorts, ANKRD28 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ANKRD28-associated genes across cancer lineages are TRIM48, NPY5R, and OR6C70. Each is linked with ANKRD28 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD28-to-partner and partner-to-ANKRD28 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD28→partner) and Y-score (partner→ANKRD28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	TRIM48 →	+0.310	+4.807	<.001	.006	3	1
BLOOD_Myeloma	NPY5R →	+0.023	+4.807	<.001	.006	3	1
BLOOD_Myeloma	OR6C70 →	+0.073	+4.807	<.001	.006	3	1
BREAST	OR10W1 →	+0.013	+5.781	<.001	.001	3	1
BREAST	OR11L1 →	+0.019	+5.169	<.001	.005	3	1
BREAST	OR14A2 →	+0.035	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

ANKRD28 survival (RNA) · tumor vs normal (RNA) · all ANKRD28 data types