ANKRD28

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANKRD28 mutation is significantly associated with the mutation status of many other genes, with 3,432 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD28-associated genes across cancer lineages are LRP4, DNAH2, and CUL7. Each is linked with ANKRD28 in more than 5 cancer types. Because this analysis shows association rather than direction, both ANKRD28-to-partner and partner-to-ANKRD28 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD28→partner) and Y-score (partner→ANKRD28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaLRP4 →+3.050+3.624.001.00116
CNSDNAH2 →+3.029+4.491.004.00415
OVARYCUL7 →+5.415+5.415.004.00415
CNSNRXN2 →+4.614+4.614.006.00615
CNSPLD2 →+4.614+4.614.006.00615
LARGE_INTESTINETOP2B →+2.263+3.392.001.00115
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,432 associations by consensus.

Exploration