ANKRD18A

Across TCGA patient cohorts, ANKRD18A mutation is significantly associated with the RNA expression of many other genes, with 2,916 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD18A-associated genes across cancer lineages are ARHGAP11A, NUSAP1, and CCL4. Each is linked with ANKRD18A in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD18A-to-partner and partner-to-ANKRD18A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARHGAP11A grouped by ANKRD18A-low versus ANKRD18A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD18A→partner) and Y-score (partner→ANKRD18A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARHGAP11A →	+0.500	+1.847	.003	.007	3	3
UCEC	NUSAP1 →	+0.567	+1.906	.001	.001	3	3
UCEC	CCL4 →	+0.733	+1.975	<.001	<.001	3	2
UCEC	RNA5SP412 →	+0.328	+1.431	.002	.007	3	2
SKCM	ATP13A5-AS1 →	+0.446	+2.498	<.001	.007	3	2
CESC	RNU6-1066P →	+0.499	+5.003	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,916 associations by consensus.

ARHGAP11A by ANKRD18A expression — UCEC

Explore this box plot interactively →