ANKRD18A

Across TCGA patient cohorts, ANKRD18A mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD18A-associated genes across cancer lineages are Rad50, ASNS, and ATM. Each is linked with ANKRD18A in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD18A-to-partner and partner-to-ANKRD18A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rad50 grouped by ANKRD18A-low versus ANKRD18A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD18A→partner) and Y-score (partner→ANKRD18A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rad50 →	-0.218	-1.643	.003	.003	3	2
UCEC	ASNS →	+0.382	+1.584	<.001	.008	3	2
UCEC	ATM →	-0.428	-2.893	.002	.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.657	+1.945	<.001	.002	3	2
UCEC	14-3-3_beta →	-0.079	-1.973	.011	.008	3	1
UCEC	EGFR_pY1068 →	-0.305	-2.169	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Rad50 by ANKRD18A expression — UCEC

Explore this box plot interactively →