ANKRD18A

Across TCGA cell cohorts, ANKRD18A mutation is significantly associated with the RNA expression of many other genes, with 451 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD18A-associated genes across cancer lineages are KCNK16, TBC1D21, and GAGE10. Each is linked with ANKRD18A in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD18A-to-partner and partner-to-ANKRD18A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNK16 grouped by ANKRD18A-low versus ANKRD18A-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD18A→partner) and Y-score (partner→ANKRD18A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	KCNK16 →	+0.151	+4.981	<.001	.008	3	2
STOMACH	TBC1D21 →	+0.076	+4.129	<.001	.007	3	2
STOMACH	GAGE10 →	+0.157	+4.129	<.001	.007	3	2
LARGE_INTESTINE	FBXL4 →	+0.577	+3.364	<.001	.002	3	2
LARGE_INTESTINE	BRDT →	+0.079	+2.584	<.001	.004	3	2
BONE	OR1L6 →	+0.020	+5.169	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 451 associations by consensus.

KCNK16 by ANKRD18A expression — CNS

Explore this box plot interactively →