ANKRD1

Across TCGA patient cohorts, ANKRD1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,414 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ANKRD1-associated genes across cancer lineages are RPUSD3, TRAIP, and KCNJ11. Each is linked with ANKRD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD1-to-partner and partner-to-ANKRD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKRD1 versus RPUSD3 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD1→partner) and Y-score (partner→ANKRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPUSD3 →	+0.810	+0.841	<.001	<.001	3	3
LSCC	TRAIP →	+0.830	+0.747	.002	.002	3	3
LSCC	KCNJ11 →	+1.133	+0.609	<.001	.005	3	3
OV	SS18L2 →	+0.552	+0.446	<.001	.003	3	3
HNSC	ATP2A1 →	+1.469	+1.016	<.001	<.001	3	3
OV	PRPF6 →	+0.526	+0.463	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,414 associations by consensus.

ANKRD1 vs RPUSD3 — BRCA

Explore this scatter interactively →