ANKHD1-EIF4EBP3

Across TCGA patient cohorts, ANKHD1-EIF4EBP3 mutation is significantly associated with the RNA expression of many other genes, with 5,498 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKHD1-EIF4EBP3-associated genes across cancer lineages are CASP6, PLA2G12AP1, and PTP4A3. Each is linked with ANKHD1-EIF4EBP3 in more than 4 cancer types. Because this analysis shows association rather than direction, both ANKHD1-EIF4EBP3-to-partner and partner-to-ANKHD1-EIF4EBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CASP6 grouped by ANKHD1-EIF4EBP3-low versus ANKHD1-EIF4EBP3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKHD1-EIF4EBP3→partner) and Y-score (partner→ANKHD1-EIF4EBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	CASP6 →	+0.404	+1.855	.007	.005	3	5
COAD	PLA2G12AP1 →	+0.522	+2.486	<.001	.009	2	5
UCEC	PTP4A3 →	-0.568	-1.256	<.001	<.001	3	4
BLCA	CMC1 →	+0.287	+3.364	.002	.004	3	4
STAD	MRPS36 →	+0.691	+3.592	<.001	.002	3	4
COAD	SHROOM4 →	-0.977	-2.700	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,498 associations by consensus.

CASP6 by ANKHD1-EIF4EBP3 expression — BLCA

Explore this box plot interactively →