ANKAR

Across TCGA patient cohorts, ANKAR RNA expression is significantly associated with the protein abundance of many other proteins, with 18,441 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ANKAR-associated proteins across cancer lineages are AGO1, LARP4_S722, and LMNB2. Each is linked with ANKAR in more than 7 cancer types. Because this analysis shows association rather than direction, both ANKAR-to-partner and partner-to-ANKAR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKAR versus AGO1 in HNSC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKAR→partner) and Y-score (partner→ANKAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	AGO1 →	+0.350	+0.744	<.001	<.001	3	8
HNSC	LARP4_S722 →	-0.476	-0.568	<.001	<.001	3	7
CCRCC	LMNB2 →	+0.281	+0.369	<.001	.001	3	7
LUAD	NCL_S67 →	-0.879	-0.447	.001	<.001	3	6
LUAD	NRDC →	-0.228	-0.487	<.001	<.001	3	6
BRCA	PDCD4 →	+0.457	+0.350	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,441 associations by consensus.

ANKAR vs AGO1 — HNSC

Explore this scatter interactively →