ANK2

Across TCGA patient cohorts, ANK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,229 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ANK2-associated proteins across cancer lineages are ANK2_S1461, ANK2_S846, and ANK2_T3814. Each is linked with ANK2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ANK2-to-partner and partner-to-ANK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANK2 versus ANK2_S1461 in HNSC, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANK2→partner) and Y-score (partner→ANK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ANK2_S1461 →	+1.096	+1.322	<.001	<.001	3	8
LSCC	ANK2_S846 →	+0.822	+0.859	<.001	<.001	3	8
LSCC	ANK2_T3814 →	+0.881	+0.898	<.001	<.001	3	8
LSCC	ANK2_S890 →	+1.047	+0.881	<.001	<.001	3	8
PDAC	ITSN1 →	+0.336	+0.786	<.001	<.001	3	8
BRCA	TLN2 →	+0.545	+0.747	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,229 associations by consensus.

ANK2 vs ANK2_S1461 — HNSC

Explore this scatter interactively →