ANAPC1P4

Across TCGA patient cohorts, ANAPC1P4 mutation is significantly associated with the RNA expression of many other genes, with 48 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ANAPC1P4-associated genes across cancer lineages are OR5AC4P, IGHVII-53-1, and NAV2-AS3. Each is linked with ANAPC1P4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANAPC1P4-to-partner and partner-to-ANAPC1P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5AC4P grouped by ANAPC1P4-low versus ANAPC1P4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC1P4→partner) and Y-score (partner→ANAPC1P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR5AC4P →	+0.062	+4.508	<.001	.001	3	1
SKCM	IGHVII-53-1 →	+0.237	+4.508	<.001	.001	3	1
SKCM	NAV2-AS3 →	+0.147	+3.952	<.001	.007	3	1
SKCM	EDDM3DP →	+0.140	+3.801	<.001	.007	3	1
SKCM	SNORA70D →	+0.216	+5.212	<.001	.002	3	1
SKCM	MIR4717 →	+0.318	+5.408	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

OR5AC4P by ANAPC1P4 expression — SKCM

Explore this box plot interactively →