AMY1B

Across TCGA patient cohorts, AMY1B mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AMY1B-associated genes across cancer lineages are MIR7155, RNU6-391P, and OR6C72P. Each is linked with AMY1B in more than 1 cancer types. Because this analysis shows association rather than direction, both AMY1B-to-partner and partner-to-AMY1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7155 grouped by AMY1B-low versus AMY1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMY1B→partner) and Y-score (partner→AMY1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7155 →	+0.854	+4.694	<.001	.007	3	1
UCEC	RNU6-391P →	+0.449	+5.027	<.001	.004	3	1
UCEC	OR6C72P →	+0.147	+5.027	<.001	.004	3	1
UCEC	LINC01809 →	+0.527	+5.943	<.001	<.001	3	1
UCEC	RNU7-90P →	+0.637	+4.771	<.001	.006	3	1
UCEC	CYCTP →	+0.473	+4.374	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

MIR7155 by AMY1B expression — UCEC

Explore this box plot interactively →