AMY1A

Across TCGA patient cohorts, AMY1A mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AMY1A-associated genes across cancer lineages are FAM71A, ERHP2, and LINC02794. Each is linked with AMY1A in more than 1 cancer types. Because this analysis shows association rather than direction, both AMY1A-to-partner and partner-to-AMY1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM71A grouped by AMY1A-low versus AMY1A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMY1A→partner) and Y-score (partner→AMY1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAM71A →	+0.046	+4.809	.006	.003	3	1
UCEC	ERHP2 →	+0.258	+4.937	<.001	.005	3	1
UCEC	LINC02794 →	+0.120	+5.038	.002	.002	3	1
UCEC	MTHFD2P3 →	+0.478	+5.474	<.001	<.001	3	1
UCEC	RN7SL454P →	+0.332	+4.423	.003	.006	3	1
UCEC	RNU7-70P →	+0.725	+4.937	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

FAM71A by AMY1A expression — UCEC

Explore this box plot interactively →