AMY1A

Across TCGA pan-cancer cohorts, AMY1A RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of AMY1A’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where AMY1A RNA is more highly expressed in tumor relative to normal tissue. In most cancer types AMY1A is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

ESCA and LUSC are the cancer types where AMY1A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AMY1A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	All	II,III,IV	+0.025	.037	3	view →
LUSC	Female	All	−0.013	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

AMY1A–ESCA

Open the ESCA breakdown →