AMT

Across TCGA patient cohorts, AMT RNA expression is significantly associated with the protein abundance of many other proteins, with 10,718 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AMT-associated proteins across cancer lineages are BRD3, CPSF7, and EPM2AIP1. Each is linked with AMT in more than 3 cancer types. Because this analysis shows association rather than direction, both AMT-to-partner and partner-to-AMT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AMT versus BRD3 in GBM, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AMT→partner) and Y-score (partner→AMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BRD3 →	+0.277	+0.199	<.001	<.001	3	4
GBM	CPSF7 →	+0.312	+0.194	<.001	<.001	3	4
BRCA	EPM2AIP1 →	+0.364	+0.111	<.001	<.001	3	4
GBM	GTF3C4_S611 →	+0.271	+0.188	.003	.003	3	4
BRCA	SRRM2_S1694 →	+0.526	+0.128	<.001	<.001	3	4
BRCA	ACIN1_S729 →	+0.604	+0.155	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,718 associations by consensus.

AMT vs BRD3 — GBM

Explore this scatter interactively →