AMT

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, AMT RNA expression is significantly associated with the go_rna of many other GO terms, with 3,036 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible AMT-associated GO terms across cancer lineages are Cilium movement involved in cell motility, Sperm motility, and Flagellated sperm motility. Each is linked with AMT in more than 13 cancer types. Because this analysis shows association rather than direction, both AMT-to-partner and partner-to-AMT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium movement involved in cell motility grouped by AMT-low versus AMT-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMT→partner) and Y-score (partner→AMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTCilium movement involved in cell motility →-0.119-0.933<.001<.001314
UPPER_AERODIGESTIVE_TRACTSperm motility →-0.122-1.594<.001<.001314
UPPER_AERODIGESTIVE_TRACTFlagellated sperm motility →-0.122-1.594<.001<.001314
UPPER_AERODIGESTIVE_TRACTCilium-dependent cell motility →-0.115-0.933<.001<.001313
UPPER_AERODIGESTIVE_TRACTCilium or flagellum-dependent cell motility →-0.115-0.933<.001<.001313
LARGE_INTESTINEChiasma assembly →+0.226+1.100<.001.002313
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,036 associations by consensus.

Cilium movement involved in cell motility by AMT expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Cilium movement involved in cell motility in AMT-low vs AMT-high samples in UPPER_AERODIGESTIVE_TRACT.

Explore this box plot interactively →

Exploration