AMN1

Across TCGA patient cohorts, AMN1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,384 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AMN1-associated genes across cancer lineages are NEFL, HUNK-AS1, and LMNA. Each is linked with AMN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both AMN1-to-partner and partner-to-AMN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AMN1 versus NEFL in GBM, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMN1→partner) and Y-score (partner→AMN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NEFL →	+2.470	+0.277	<.001	<.001	3	3
UCEC	HUNK-AS1 →	+0.419	+0.412	.006	<.001	3	2
GBM	LMNA →	-0.357	-0.219	.001	<.001	3	2
CCRCC	C5orf64 →	-0.038	-0.199	.003	.004	3	2
LUAD	MIR877 →	-0.399	-0.325	.004	.008	3	2
CCRCC	TRIM60P17 →	-0.824	-0.206	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,384 associations by consensus.

AMN1 vs NEFL — GBM

Explore this scatter interactively →