AMIGO2

Across TCGA patient cohorts, AMIGO2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,973 significant associations in total. OV shows the largest number of these associations.

The most reproducible AMIGO2-associated genes across cancer lineages are CALU, PDLIM7, and ELF4. Each is linked with AMIGO2 in more than 2 cancer types. Because this analysis shows association rather than direction, both AMIGO2-to-partner and partner-to-AMIGO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AMIGO2 versus CALU in OV, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMIGO2→partner) and Y-score (partner→AMIGO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CALU →	+0.974	+0.847	<.001	<.001	3	3
OV	PDLIM7 →	+0.953	+0.634	<.001	<.001	3	3
HNSC	ELF4 →	+0.619	+0.791	.001	.004	3	2
HNSC	TESK1 →	+0.803	+1.152	.007	.001	3	2
OV	MMD →	+0.896	+0.682	<.001	.001	3	2
LUAD	DAP →	+0.618	+0.436	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,973 associations by consensus.

AMIGO2 vs CALU — OV

Explore this scatter interactively →