AMIGO1

Across TCGA patient cohorts, AMIGO1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,143 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AMIGO1-associated proteins across cancer lineages are PLAU, UPP1, and PGAM1_S31. Each is linked with AMIGO1 in more than 6 cancer types. Because this analysis shows association rather than direction, both AMIGO1-to-partner and partner-to-AMIGO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AMIGO1 versus PLAU in CCRCC, with a Pearson correlation of -0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AMIGO1→partner) and Y-score (partner→AMIGO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PLAU →	-0.905	-1.119	.001	.002	3	7
GBM	UPP1 →	-0.767	-0.654	<.001	<.001	3	6
HNSC	PGAM1_S31 →	-0.537	-0.829	<.001	<.001	3	6
GBM	PKP4 →	+0.363	+0.605	.001	.007	3	6
LUAD	PPP1R18_S224 →	-0.475	-0.574	.003	<.001	3	6
HNSC	DDAH1 →	+0.622	+0.690	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,143 associations by consensus.

AMIGO1 vs PLAU — CCRCC

Explore this scatter interactively →