ALKBH7

Across TCGA patient cohorts, ALKBH7 mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALKBH7-associated genes across cancer lineages are RN7SL301P, MIR6780B, and WBP1LP6. Each is linked with ALKBH7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ALKBH7-to-partner and partner-to-ALKBH7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL301P grouped by ALKBH7-low versus ALKBH7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKBH7→partner) and Y-score (partner→ALKBH7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL301P →	+0.295	+3.546	<.001	<.001	3	1
UCEC	MIR6780B →	+0.537	+3.567	<.001	.001	3	1
UCEC	WBP1LP6 →	+0.112	+4.437	<.001	.005	3	1
SKCM	IQCF5-AS1 →	+0.024	+5.362	<.001	.005	3	1
SKCM	RN7SKP210 →	+0.378	+6.080	<.001	.002	3	1
SKCM	OR7E129P →	+0.069	+5.224	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

RN7SL301P by ALKBH7 expression — UCEC

Explore this box plot interactively →