ALKBH4

Across TCGA patient cohorts, ALKBH4 protein abundance is significantly associated with the RNA expression of many other genes, with 7,989 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALKBH4-associated genes across cancer lineages are PTCD1, ZNF394, and RINT1. Each is linked with ALKBH4 in more than 5 cancer types. Because this analysis shows association rather than direction, both ALKBH4-to-partner and partner-to-ALKBH4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALKBH4 versus PTCD1 in HNSC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKBH4→partner) and Y-score (partner→ALKBH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PTCD1 →	+0.443	+0.345	.005	<.001	3	6
HNSC	ZNF394 →	+0.391	+0.265	<.001	<.001	3	6
HNSC	RINT1 →	+0.640	+0.284	<.001	<.001	3	6
HNSC	DLD →	+0.610	+0.301	.001	<.001	3	6
HNSC	PEX1 →	+0.912	+0.387	<.001	<.001	3	5
HNSC	FAM200A →	+0.819	+0.448	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,989 associations by consensus.

ALKBH4 vs PTCD1 — HNSC

Explore this scatter interactively →