ALKBH3

Across TCGA patient cohorts, ALKBH3 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,707 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALKBH3-associated proteins across cancer lineages are POU2F2, TRIP6, and MNDA. Each is linked with ALKBH3 in more than 3 cancer types. Because this analysis shows association rather than direction, both ALKBH3-to-partner and partner-to-ALKBH3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALKBH3 versus POU2F2 in BRCA, with a Pearson correlation of -0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKBH3→partner) and Y-score (partner→ALKBH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	POU2F2 →	-0.948	-0.640	.001	.008	3	4
BRCA	TRIP6 →	+0.336	+0.665	<.001	.001	3	3
GBM	MNDA →	-0.841	-0.182	<.001	.003	3	3
GBM	NCF4 →	-0.621	-0.207	.001	.005	3	3
LUAD	ARHGAP1 →	+0.299	+0.506	<.001	<.001	3	3
CCRCC	COX6A1 →	-0.359	-0.236	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,707 associations by consensus.

ALKBH3 vs POU2F2 — BRCA

Explore this scatter interactively →