ALKBH3

Across TCGA patient cohorts, ALKBH3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,257 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ALKBH3-associated genes across cancer lineages are SEC14L1P1, ALKBH3-AS1, and CPED1. Each is linked with ALKBH3 in more than 3 cancer types. Because this analysis shows association rather than direction, both ALKBH3-to-partner and partner-to-ALKBH3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALKBH3 versus SEC14L1P1 in UCEC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKBH3→partner) and Y-score (partner→ALKBH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SEC14L1P1 →	+0.867	+0.451	.001	.004	3	4
LUAD	ALKBH3-AS1 →	+0.406	+0.189	<.001	.007	3	4
UCEC	CPED1 →	+0.915	+0.355	<.001	.005	3	3
UCEC	ACTA2 →	+1.764	+0.394	.002	.006	3	3
UCEC	PLSCR4 →	+1.055	+0.613	.006	.001	3	3
LUAD	PDLIM2 →	+0.454	+0.275	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,257 associations by consensus.

ALKBH3 vs SEC14L1P1 — UCEC

Explore this scatter interactively →