ALG10B

Across TCGA patient cohorts, ALG10B mutation is significantly associated with the RNA expression of many other genes, with 2,861 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALG10B-associated genes across cancer lineages are LINC02730, HMX2, and IGHD3-22. Each is linked with ALG10B in more than 1 cancer types. Because this analysis shows association rather than direction, both ALG10B-to-partner and partner-to-ALG10B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02730 grouped by ALG10B-low versus ALG10B-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG10B→partner) and Y-score (partner→ALG10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	LINC02730 →	+0.048	+4.423	<.001	.007	3	2
UCEC	HMX2 →	+0.778	+2.360	<.001	<.001	3	2
LIHC	IGHD3-22 →	+0.760	+3.915	.007	.005	3	2
BLCA	PUDPP1 →	+0.075	+4.082	<.001	.002	3	2
LUAD	RNU6-15P →	+0.403	+4.137	<.001	.001	3	2
UCEC	LINC01281 →	+0.207	+2.223	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,861 associations by consensus.

LINC02730 by ALG10B expression — LIHC

Explore this box plot interactively →