ALG10B

Across TCGA cell cohorts, ALG10B mutation is significantly associated with the RNA expression of many other genes, with 107 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ALG10B-associated genes across cancer lineages are PRAMEF2, OR4D6, and MRAP. Each is linked with ALG10B in more than 1 cancer types. Because this analysis shows association rather than direction, both ALG10B-to-partner and partner-to-ALG10B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF2 grouped by ALG10B-low versus ALG10B-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG10B→partner) and Y-score (partner→ALG10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	PRAMEF2 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	OR4D6 →	+0.013	+4.906	<.001	.006	3	1
UPPER_AERODIGESTIVE_TRACT	MRAP →	+0.028	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	TGIF2LY →	+0.148	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	IZUMO1R →	+0.053	+4.736	<.001	.009	3	1
STOMACH	FERD3L →	+0.102	+4.285	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 107 associations by consensus.

PRAMEF2 by ALG10B expression — OESOPHAGUS

Explore this box plot interactively →